| Animal bacterial diseases have always been a great problem perplexing veterinary clinic and livestock and poultry breeding. The spread ability of bacterial diseases and resistance mutation capacity make clinical antibacterial drug difficult to take a step. In addition, drug residues caused by unreasonable prescription not only harm animal and human health, but also cause huge economic losses to livestock farmers. Rapid diagnosis of animal bacterial diseases is one of the prerequisites to prevent the spread of bacteria, also the basis of formulating rational drug use plan. Microbial detection is the main technique for rapid diagnosis of animal bacterial diseases. The traditional microbial detection technology is still the mainstream method at this stage. However, as bacteria continue to mutate and the living environment continues to change, traditional methods are not enough to deal instantly with the diversity of bacteria and the lack of antibacterial drugs. The continuous innovation of microbial detection technology has also produced many emerging technologies to meet clinical needs with the development of science and technology, which can not only rapidly diagnose animal bacterial diseases, distinguish the number of live and dead bacteria, but also intuitively reflect the interaction between bacteria and drugs. This review systematically summarized the traditional detection methods to more rapid and accurate detection techniques based on nucleic acid, protein, bacterial spectral characteristics, etc. At the same time, it also expanded and proposed the clinical microbial detection needs of host-oriented therapeutic regimen. The review of microbial detection technology in this paper provides methods for clinical diagnosis of animal bacterial diseases, and provides the best scheme for veterinary clinical precision medication. |
