Enveloped viruses refer to viruses with a lipid bilayer membrane, such as influenza viruses, coronaviruses, etc., which cause many serious diseases worldwide annually and seriously threaten human health. The use of antiviral drugs is the main strategy for the prevention and treatment of viral infections, and Bacillus and its metabolites can inhibit infection with a variety of enveloped viruses. This article reviews the important roles played by crude extracts, peptides, enzymes, extracellular polymers, small double-stranded RNA and heat-inactivated Bacillus subtilis spores in anti-enveloped virus infection, and the mechanism is to directly destroy the viral envelope, prevent membrane fusion, directly pair with viral genomic RNA, catalyze the lysis of viral RNA, activate the natural immune response, etc., hopefully to provide a reference for the continuous prevention and treatment of enveloped virus. |