Polylactic acid (PLA) has attracted much attention due to its good physicochemical properties, biocompatibility and biodegradability, and has been considered as the most promising alternative to existing petroleum-based plastics. However, the problem of slow degradation and long cycle time still exists in practical applications, so in-depth research on the biodegradation of PLA is essential to solve plastic waste pollution and alleviate energy crisis. In recent years, the research on PLA biodegradation by microorganisms (actinomycetes, bacteria and fungi) and enzymes (protease, lipase, esterase and cutinase) has made some progress. This work reviews the research progress of PLA biodegradation in degradation microorganisms, degradation enzymes and degradation mechanisms, and provides an outlook on the future trends of PLA biodegradation research. |