In human intestines harbors diverse microbes, called intestinal microbial community (IMC), they play the most important role in the health of their host. The constituents of IMC includes bacteria, viruses, and eucaryotic organisms, they have been proved to have close relation with the host′s health, especially probiotics. Probiotics play their role through many pathways, including the interaction with the host′s microbes, to resist the setting of pathogen, to improve the function of preventive screen of intestines, to regulate the function of immunity, to produce correlated metabolites, they play beneficial role in host′s metabolism, immunity, and nervous system. This paper summarizes the functional mechanism of probiotics, discusses the recent clinical study application cases of probiotics so as to better understand the distribution of probiotics on the risk of diseases and the sustainability of health, and will point out a road for new therapeutic interfering in and diseases prevention tactics. |