| Myeloma cells and single B cells can be fused to form hybridoma cells, after isolation and cloning can produce antibodies against a single epitope and have the same structure and function, namely monoclonal antibody (mAb). The development of monoclonal antibody has gone through four stages. Its preparation technology is also being steadily renovated and developed. At present, monoclonal antibody technology is becoming more and more mature, and plays a key role in the treatment and diagnosis of diseases. Monoclonal antibodies differ from natural antibodies in that they have high valence, strong specificity, little cross reaction, and can be prepared in great quantity, with high targeting, and other features. mAb can be used to diagnose and treat infectious diseases, autoimmune diseases and cancers etc. In this summary, the development course of mAb and its applications in anti infectious diseases were briefly expatiated. |
