文章摘要
2013至2017年4 542例泌尿生殖系感染者NG、CT和UU感染特点分析
Infection Features Analysis of Neisseria gonorrhoeae, Chlamydia trachomatis, and Ureaplasma urealyticum in 4 542 Cases Infectors of the Urogenital System in 2013-2017
  
DOI:doi:10.3969/j.issn.1005-7021.2019.04.013
中文关键词: 性传播疾病  淋球菌  沙眼衣原体  解脲脲原体  感染特点
英文关键词: STD  Neisseria gonorrhoeae(NG)  Chlamydia trachomatis(CT)  Ureaplasma urealyticum(UU)  infection characteristics
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作者单位
何学虎 1.宁夏医科大学总医院 医学实验中心宁夏 银川 7500042.宁夏临床病原微生物重点实验室宁夏 银川 750004 
梁小燕 宁夏医科大学总医院 医学实验中心宁夏 银川 750004 
董洁 宁夏医科大学总医院 医学实验中心宁夏 银川 750004 
赵倩颖 宁夏医科大学总医院 医学实验中心宁夏 银川 750004 
赵玥 宁夏医科大学总医院 医学实验中心宁夏 银川 750004 
郭雅琪 宁夏医科大学总医院 医学实验中心宁夏 银川 750004 
师志云 1.宁夏医科大学总医院 医学实验中心宁夏 银川 7500042.宁夏临床病原微生物重点实验室宁夏 银川 750004 
张玉英 宁夏医科大学总医院 医学实验中心宁夏 银川 750004 
赵志军 1.宁夏医科大学总医院 医学实验中心宁夏 银川 7500042.宁夏临床病原微生物重点实验室宁夏 银川 750004 
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中文摘要:
      探讨淋球菌(NG)、沙眼衣原体(CT)和解脲脲原体(UU)三种性传播疾病(STD)病原体在宁夏泌尿生殖系感染者中的感染状况,为临床防治提供参考。选取2013年1月至2017年12月在宁夏医科大学总医院就诊的患者4 542例,其中男性3 561例,女性981例,应用实时荧光PCR法检测上述病原体,并分析结果。3种病原体总感染率为26.51%(1 204/4 542),NG、CT、UU单一病原体感染率分别为26.31%、15.21%和35.70%,男、女感染率分别为23.48%和37.51%,感染率有性别差异(P<0.01),NG、CT感染率男性显著高于女性,UU感染率女性显著高于男性;混合感染率为3.32%(151/4 542),男、女混合感染率分别为3.82%和153%,主要以CT+UU为主,NG+UU次之;从年龄分布来说,男性≤20岁年龄段感染率最高,女性21~30岁年龄段感染率最高;5年来NG、CT和UU感染率呈上升趋势。泌尿生殖系感染者中NG、CT、UU感染情况严重,男性易感NG和CT,女性易感UU,同时,混合感染也较常见,提示应同时检测多种病原体以防漏检。
英文摘要:
      The infection situation of three sexually transmitted diseases (STD) pathogens of Neisseria gonorrhoeae(NG), Chlamydia trachomatis(CT) and Ureaplasma urealyticum(UU) in patients with urogenital infection in Ningxia was investigated and provided the evidence for clinical prevention and treatment. A total of 4 542 outpatient cases in the hospital from 2013 to 2017 were chosen in this study. NG, CT, and UU were detected and analyzed in 3 561cases of male and 981 cases of female by real time fluorescence PCR and analyzed the results. The overall infection rate was 26.51% (1 204/4 542) NG, CT, and UU single pathogen infection rates were 26.31%, 15.21%, and 35.70% respectively, the infection rate of male was 23.48% and that of female was 37.51%, which have gender differences (P<0.01), the infection rate of NG and CT in male were significantly higher than that of female, and the infection rate of UU in male were significantly lower than that of female. The mixed infection rate was 3.32% (151/4 542) 3.82% for male and 1.53% for female, and the mixed infection type was mainly CT+UU, followed by NG+UU. In terms of age distribution, males at age 20 or less and females at age 21 to 30 had the highest infection rates. Overall, NG, CT, and UU infection rates have been on the rise in the last 5 years. The infection of NG, CT, and UU in patients with urogenital infection was serious, males were susceptible to NG and CT, and females were susceptible to UU. Meanwhile, mixed infection were also comparatively common, suggested that multiple pathogens should be detected simultaneously to avoid missed detection.
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